Penn State (2-3) at No. 8 Loyola (3-0) — Saturday, 12 p.m. (ESPN+)
Loyola has had a week and a half layover after rallying to beat Johns Hopkins, but Penn State has had all of three days to stew about a 10-8 loss to Drexel.
Virginia Tech (4-1) at No. 1 Boston College (5-1) — Sunday, 11 a.m. (ACCX)
Whether Boston College is a lame-duck No. 1 is for us to discuss — the Eagles are focusing on rebounding from a title-game rematch loss to Northwestern against a Hokies team off to a hot start.
Yale (3-0) at No. 18 Princeton (2-1) — Saturday, 12 p.m. (ESPN+)
Yale beat Princeton twice, including by one goal in the Ivy League championship semifinal, so expect a revenge mindset when the Tigers host the Bulldogs on Saturday.
Duke (3-3) at No. 6 Syracuse (2-2) — Saturday, 12 p.m. (ACCX)
The Orange returns home to the Dome as one of the nation’s hottest teams having downed rival Notre Dame in come-from-behind fashion last weekend in South Bend.
Brown (3-0) at Harvard (3-0) — Saturday, 12 p.m. (ESPN+)
One of the pleasant surprises this season, Brown is off to a 3-0 start under new coach Katrina Dowd, but so is Harvard under the tutelage of one of the game’s G.O.A.T. goalies, Devon Wills.
No. 16 USC (3-1) at 14 Johns Hopkins (4-2) — Sunday, 1 p.m., (Centennial Digital Network)
The Blue Jays are coming off back-to-back one-goal games (a loss to Penn and a win over Georgetown), while USC is attempting to bounce back after mustering three goals against a stout Michigan defense.
No. 15 Virginia (4-1) at No. 19 Clemson (4-0) — Saturday, 1 p.m. (ACCX)
Two programs who are looking to break through in the BC-UNC-Syracuse-dominated ACC square off inside Clemson’s 1,000-seat stadium just for women’s lacrosse.
Richmond (4-0) at No. 17 Navy (4-0) — Saturday, 4 p.m. (ESPN+)
A pair of Mid-Atlantic teams with identical records match up in defending A-10 tournament champion Richmond and a Navy team hanging tough without star Ava Yovino in the lineup.
No. 10 Florida (2-2) at Arizona State (3-2) — Sunday, 1 p.m. (ASU Live Stream)
After an overtime win over Maryland and a rout of Jacksonville on Wednesday, the swagger is back for the Gators.